原著論文

効率的かつ劇的な反応加速効果をもたらす有機分子触媒システムの開発

萬代大樹*,藤居一輝,菅 誠治* 有機合成化学協会誌,Vol. 75 (2017) No. 6 p. 632-649 DOI: [...]

Desymmetrization of meso-1,2-Diols by a Chiral N,N-4-Dimethylaminopyridine Derivative Containing a 1,1′-Binaphthyl Unit: Importance of the Hydroxy Groups

Hiroki Mandai* , Hiroshi Yasuhara, Kazuki Fujii, Yukihito Shimomura, Koichi Mitsudo , and Seiji Suga* J. Org. Chem., ASAP DOI: [...]

Synthesis of 3-Benzo[b]thienyl 3-Thienyl Ether via an Addition–Elimination Reaction and Its Transformation to an Oxygen-Fused Dithiophene Skeleton: Synthesis and Properties of Benzodithienofuran and Its π-Extended Derivatives

Koichi Mitsudo,* Yuji Kurimoto, Hiroki Mandai, and Seiji Suga* Org. Lett. 2017, 19, 2821–2124. DOI: [...]

Rh-Catalyzed Dehydrogenative Cyclization Leading to Benzosilolothiophene Derivatives via Si–H/C–H Bond Cleavage

Koichi Mitsudo,* Seiichi Tanaka, Ryota Isobuchi, Tomohiro Inada, Hiroki Mandai, Toshinobu Korenaga, Atsushi Wakamiya, Yasujiro Murata, Seiji Suga* Org. Lett. [...]

Hydrogen Bonding-Assisted Enhancement of the Reaction Rate and Selectivity in the Kinetic Resolution of d,l-1,2-Diols with Chiral Nucleophilic Catalysts

Kazuki Fujii,  Koichi Mitsudo, Hiroki Mandai,* Seiji Suga* Adv. Synth. Catal. 2017, in press. Selected as VIP. DOI: 10.1002/adsc.201700057 Front [...]

AN INTRAMOLECULAR NUCLEOPHILE-CATALYZED ALDOL-LACTONIZATION (NCAL) REACTION OF S-ARYL-(E)-6-OXOHEX-2-ENETHIOATE WITH N,N-4-DIMETHYLAMINOPYRIDINE N-OXIDE

Hiroki Mandai,* Keita Shimowaki, Kohei Hongo, Koichi Mitsudo, Seiji Suga* Heterocycles 2017, 94, 492-502. DOI: [...]

Magnetic Attachment of Lipase Immobilized on Bacteriogenic Iron Oxide Inside a Microtube Reactor for the Kinetic Resolution of Secondary Alcohols

Kyoko Mandai, Takehiro Fukuda, Yuki Miyazaki, Hideki Hashimoto, Hiroki Mandai, Tadashi Ema, Jun Takada, Seiji Suga* Synlett. 2017, in [...]

Facile Synthesis of Naphthothiophenone Derivatives and Anthradithiophenedione via Friedel-Crafts Acylation and Their Fundamental Properties

Koichi Mitsudo,* Takashi Murakami, Takuya Shibasaki, Tomohiro Inada, Hiroki Mandai, Hiromi Ota, Seiji Suga* Synlett 2016, 27, 2327–2332. DOI: [...]

Synthetic Terrein Inhibits Progression of Head and Neck Cancer by Suppressing Angiogenin Production

Akane Shibata, Soichiro Ibaragi,* Hiroki Mandai, Toki Tsumura, Koji Kishimoto, Tatsuo Okui, Nur Mohammad Monsur Hassan, Tsuyoshi Shimo, Kazuhiro Omori, Guo-Fu [...]